Florin Grigorescu, MD, PhD

Doctor Florin Grigorescu is the leader of molecular genetics team at university of Montpellier, France known as endocrinologist and nutritionist for his contribution in purification of insulin receptor kinase from human erythrocyte and identification of defects in genetic syndrome of severe insulin resistance with Acanthosis Nigricans. Retiring as researcher from INSERM in 2019, he is currently fellow of the Institute Convergences Migrations (ICM) at Collège de France and from 2003, honorary professor for genetics at Carol Davila university, Bucharest Romania. Awarded with JB Morganni medal in Italy (Padova) in 1986 and by the National Academy of Medicine in Paris in 2001, he oriented research towards genetics of complex disorders like metabolic syndrome and polycystic ovary syndrome (PCOS) in women, searching for culprit genes by fine-scale haplotype mapping and whole genome screening. In the last several years he coordinated the MEDIGENE European program (awarded by Etoiles de l’Europe prize in 2017) over Mediterranean countries on insulin resistance using combined approaches in population genetics and genetic anthropology and is continuing collaboration with several countries in the field of genetics of insulin resistance and growth.

At INSERM he studied molecular mechanisms of insulin receptor activation using synthetic phosphorylated peptides contributing to understanding the cognitive surface of insulin receptor and IRS-1 in cellular signaling. He also described the first mutation in IGF-1 receptor gene and contributed to the description of FTO gene in PCOS. Florin Grigorescu settled the Laboratory of Molecular Endocrinology in Montpellier, France contributing to the discovery of genes involved in Berardinelly-Seip Congenital Lipodysptophy and Alström syndrome. By new strategies using single nucleotide variations (SNV) and haplotype reconstruction his current interest is focused on genetic variation in native and immigrant populations in Europe explaining metabolic alterations, effects on life span and interaction with nutritional factors explored by a novel program (MEDIPAD) for nutritional investigation in Mediterranean populations.

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Invited speakers

Main topics

  • Early feeding and growth
  • First 1000 days
  • Biological models in growth
  • Growth disorders
  • Birth cohorts
  • Croatian Islands' Birth Cohort Study (CRIBS)
  • Obesity, diabetes and metabolic syndrome
  • Nutrition and body composition
  • Epigenetics of growth and development
  • Environmental effects on growth
  • Recent advances in data analysis
  • Clinical considerations in fetal growth and neonatology
  • Kinesiology, maturity and athletic performance
  • Complex and genetic disorders
  • The exposome and allergic diseases
  • Growth and development in educational context (in collaboration with Education and Teacher Training Agency - in Croatian)

 

 

 

Important dates

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Important info

The COVID-19 pandemic has forced us to postpone the ISGA Congress, originally planned for May 27-31 2020 in Šibenik, Croatia. Even with the vaccinations, the situation is not improving significantly and prevents us from holding the Congress in 2021.

International Society for the Study of Human Growth and Clinical Auxology (ISGA), with the Institute and Anthropological Research as host, and European Anthropological Association (EAA) came to a mutual decision to hold a joint ISGA & EAA Congress in 2024 in Croatia. We look forward to this event as a great opportunity for the exchange of knowledge and networking!

As the planning for the 2024 Congress proceeds, we will be updating the website to keep you informed, so please check the website and do not hesitate to contact us if you require further information.

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